Depression
Major depressive disorder, persistent depressive disorder, and treatment-resistant depression.
Therapy
The most-studied talk therapy for depression, anxiety, and substance use.
Cognitive Behavioral Therapy (CBT) is a structured, evidence-based therapy that targets the link between thoughts, feelings, and behavior to change unhelpful patterns.
CBT is the most-studied psychotherapy for depression, anxiety, and substance use. It works by identifying the thoughts and behaviors that keep a problem going — catastrophic thinking, avoidance, withdrawal — and practicing more workable responses, both in session and as between-session homework.
At Manifest, CBT runs through both individual sessions and group skills work in PHP and IOP. For anxiety we add graded exposure; for depression we pair it with behavioral activation; for substance use we fold in relapse-prevention skills. It is delivered by trained clinicians as one tool within an integrated plan, not in isolation.